Histone H3K27Me2 (23-34) (trifluoroacetate salt)

Histone H3K27Me2 (23-34) (trifluoroacetate salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28142-1 1 mg -

6 - 10 business days*

374.00€
 
Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid... more
Product information "Histone H3K27Me2 (23-34) (trifluoroacetate salt)"
Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Dimethylation of H3K27 is present on large chromatin domains across approximately 70% of total histone H3 and prevents firing of non-cell type-specific enhancers. H3K27Me2 accumulates in gene bodies of genes with low levels of expression in mouse embryonic stem cells. Histone H3K27Me2 (23-34) has been used in epitope mapping of the lupus-derived monoclonal antibody BT164.Formal Name: L-lysyl-L-alanyl-L-alanyl-L-arginyl-N6,N6-dimethyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycine, trifluoroacetate salt. Synonyms: [Lys(Me2)27]-Histone H3 (23-34), Histone H3 (23-34) (Lys27me2), KAAR-K(Me2)-SAPATGG. Molecular Formula: C48H87N17O15 . XCF3COOH. Formula Weight: 1142.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: CN(C)CCCC[C@@H](C(N[C@@H](CO)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(O)=O)=O)=O)=O)C)=O)=O)C)=O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N[H])=O)C)=O)C)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C48H87N17O15.C2HF3O2/c1-25(57-41(74)30(50)14-8-10-18-49)38(71)56-26(2)39(72)60-32(16-12-19-53-48(51)52)42(75)61-31(15-9-11-20-64(6)7)43(76)62-33(24-66)44(77)59-28(4)47(80)65-21-13-17-34(65)45(78)58-27(3)40(73)63-37(29(5)67)46(79)55-22-35(68)54-23-36(69)70,3-2(4,5)1(6)7/h25-34,37,66-67H,8-24,49-50H2,1-7H3,(H,54,68)(H,55,79)(H,56,71)(H,57,74)(H,58,78)(H,59,77)(H,60,72)(H,61,75)(H,62,76)(H,63,73)(H,69,70)(H4,51,52,53),(H,6,7)/t25-,26-,27-,28-,29+,30-,31-,32-,33-,34-,37-,/m0./s1. InChi Key: DTIUMEJOLNFAMY-IVCKIZDSSA-N.
Keywords: [Lys(Me2)27]-Histone H3 (23-34), Histone H3 (23-34) (Lys27me2), KAAR-K(Me2)-SAPATGG, L-lysyl-L-alanyl-L-alanyl-L-arginyl-N6,N6-dimethyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycine, trifluoroacetate salt
Supplier: Cayman Chemical
Supplier-Nr: 28142

Properties

Application: DImethylated peptide fragment
Conjugate: No
MW: 1142.3 D
Formula: C48H87N17O15 . XCF3COOH
Purity: >95%
Format: Solid

Database Information

KEGG ID : K11253 | Matching products
UniProt ID : P68431 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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