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Item number: Cay27411-500
Biotin-amyloid-beta (1-40) (biotin-Abeta40) is an affinity probe that allows amyloid-beta (1-40) (Abeta40) to be detected or immobilized through interaction with the biotin ligand. It has been used to characterize Abeta40 distribution amongst the lipoprotein fractions and identify Abeta40 interaction partners in...
|Keywords:||,Biotin-Abeta40,, Biotin-Abeta (1-40),...|
Item number: Cay27420-5
YVAD-CHO is an inhibitor of caspase-1/interleukin-1beta converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO (Cay-10016). It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan (CPT-11, Cay-14180) in 4B1 cells when used at a concentration of 600...
|Keywords:||H-Tyr-Val-Ala-Asp-CHO, L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-L-alaninamide, trifluoroacetate salt|
Item number: Cay27425-500
Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. It is a non-selective caspase inhibitor.
|Keywords:||Ac-AAVALLPAVLLALLAP-VAD-aldehyde, Ac-AAVALLPAVLLALLAPVAD-CHO, Caspase Inhibitor II,...|
|Application:||Cell-permeable non-selective caspase inhibitor|
Item number: Cay27437-5
Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 µM) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells. It also inhibits caspase-6-like activity...
Item number: Cay27435-500
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. It reduces IL-1beta and IL-18 secretion in isolated mouse peritoneal macrophages stimulated by cholesterol-treated recombinant pneumolysin protein (rPLY) when used at a concentration of 30 µM. Z-YVAD-CMK reduces caspase-3 activation by the EGF-like domain of...
|Keywords:||Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV,...|
|Application:||Caspase-1 / caspase-3 inhibitor|
Item number: Cay27510-500
Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhibits replication of tobacco mosaic virus (TMV) in local lesion and leaf-disc assays (IC50s = 19.7...
|Keywords:||Malformin A1, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-isoleucyl), cyclic (1->2)-disulfide|
|Application:||Bioactive cyclopentapeptide fungal metabolite|
Item number: Cay27516-1
Histone H3K9Ac (1-24) is a peptide fragment that corresponds to amino acid residues 2-25 of the human histone H3 sequence. Acetylation of histone H3 at lysine 9 is associated with active gene transcription and can recruit the super elongation complex to chromatin through direct binding with the AF9 and ENL subunits....
|Keywords:||[Lys(Ac)9]-Histone H3 (1-24), ARTKQTAR-K(Ac)-STGGKAPRKQLATKA,...|
Item number: N2176-01.5
Sequence (linear): Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2, Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to...