Peptides

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Heparin-binding Peptide (trifluoroacetate salt)
Heparin-binding Peptide (trifluoroacetate salt)

Item number: Cay39725-1

Heparin-binding peptide is a synthetic peptide fragment corresponding to residues 1,892-1,899 of the C-terminal heparin-binding domain of fibronectin. It induces focal adhesion formation in pre-spread human embryonic fibroblasts (HEFs) when used at concentrations ranging from 1 to 1,000 µg/ml. Heparin-binding...
Keywords: Fibronectin Adhesion-promoting Peptide, Fibronectin Peptide V, FN-C/H-V,...
Application: Fibronectin peptide fragment
MW: 1023.2 D
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Kassinin (frog) (trifluoroacetate salt)
Kassinin (frog) (trifluoroacetate salt)

Item number: Cay39727-1

Kassinin is a tachykinin neuropeptide and agonist of the neurokinin-2 (NK2) and NK3 receptors. It is selective for the NK2 and NK3 receptors over the NK1 receptor. Kassinin (1 µM) increases the short-circuit current in isolated frog skin. It induces contractions in isolated guinea pig ileum and isolated rabbit...
Application: Tachykinin neuropeptide
MW: 1334.6 D
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Buccalin A (trifluoroacetate salt)
Buccalin A (trifluoroacetate salt)

Item number: Cay39728-1

Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10...
Keywords: (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxyme...
Application: Neuropeptide
MW: 1053.2 D
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PF-05190457
PF-05190457

Item number: Cay40142-1

PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Keywords: 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi...
Application: GHS-R inverse agonist
CAS 1334782-79-4
MW: 512.7 D
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[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)
[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)

Item number: Cay40149-1

[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
Keywords: [pGlu4]-MBP Peptide,...
Application: PKC peptide substrate
MW: 1373.6 D
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Malantide (trifluoroacetate salt)
Malantide (trifluoroacetate salt)

Item number: Cay40150-1

Malantide is a synthetic peptide derived from the beta-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC. Upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity. Malantide displays an emission at 302 nm...
Keywords: L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-serylglycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-...
Application: Fluorescent PKA / PKC substrate
MW: 1633.9 D
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Myomodulin A (Aplysia, Lymnaea) (trifluoroacetate salt)
Myomodulin A (Aplysia, Lymnaea) (trifluoroacetate salt)

Item number: Cay40151-1

Myomodulin A is a gastropod neuropeptide. It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve. Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal...
Keywords: MMa, MYOMOD1, Pro-Met-Ser-Met-Leu-Arg-Leu-NH2, L-prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide,...
Application: Gastropod neuropeptide
MW: 846.1 D
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Semaglutide (sodium salt)
Semaglutide (sodium salt)

Item number: Cay40170-10

Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Keywords: L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s...
Application: GLP-1R agonist
CAS 2924330-56-1
MW: 4113.6 D
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Semaglutide
Semaglutide

Item number: Cay40231-1

Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Application: GLP-1R agonist
CAS 910463-68-2
MW: 4113.6 D
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NucView(R) 488 Caspase-3 Substrate, 1mM in DMSO
NucView(R) 488 Caspase-3 Substrate, 1mM in DMSO

Item number: BOT-10402

NucView(R) 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time. Unlike conventional caspase assays, NucView(R) 488 Caspase-3 Substrate detects caspase-3/7 activity within individual intact cells without...
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NucView(R) 488 Caspase-3 Substrate, 1mM in 1X PBS
NucView(R) 488 Caspase-3 Substrate, 1mM in 1X PBS

Item number: BOT-10403

NucView(R) 488 Caspase-3 Substrate is a novel fluorogenic caspase substrate for real-time detection of caspase-3/7 activity in live cells. In apoptotic cells, the substrate is cleaved to release a DNA dye that stains the nucleus with bright green fluorescence. 1 mM in PBS, 100 uL.
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Ac-DEVD-CHO, Caspase-3 Inhibitor (5 mg)
Ac-DEVD-CHO, Caspase-3 Inhibitor (5 mg)

Item number: BOT-10404

Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for Caspase-3/7, and contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibit Caspase-3/7 activity in apoptotic cells, and to study events downstream of Caspase-3/7 activation.Soluble in DMSOStore at 4°CC20H30N4O11MW:...
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