Wnt3a/Wnt-3a (recombinant human)

Wnt3a/Wnt-3a (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH033972.10 10 µg -

7 - 16 business days*

275.00€
E-PKSH033972.50 50 µg -

7 - 16 business days*

824.00€
 
Protein Construction: Recombinant Human Protein Wnt-3a is produced by our Mammalian expression... more
Product information "Wnt3a/Wnt-3a (recombinant human)"
Protein Construction: Recombinant Human Protein Wnt-3a is produced by our Mammalian expression system and the target gene encoding Ser19-Lys352 is expressed with a fusion design at the N-terminus. Sequence: Ser19-Lys352. Fusion tag: 0 Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 110-120 kDa. Protein function: Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro). Protein function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20093360, PubMed:21244856, PubMed:24841207, PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720). [The UniProt Consortium]
Keywords: WNT3A, Protein Wnt-3a, Recombinant Human Wnt3a/Wnt-3a
Supplier: Elabscience
Supplier-Nr: E-PKSH033972

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
MW: 105.9 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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