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Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Single polypeptide chain containing 157 amino acids.
Keywords: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2 |
Supplier: | Biomol GmbH |
Supplier-Nr: | 52624.1 |
Properties
Application: | Cell culture |
Conjugate: | No |
Expressed in: | E.coli |
Origin: | Mouse |
MW: | 17300 D |
Purity: | >97% |
Database Information
KEGG ID : | K03156 | Find alternatives |
UniProt ID : | P06804 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |