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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH032000.10 | 10 µg | - |
7 - 16 business days* |
73.00€
|
|||
E-PKSH032000.50 | 50 µg | - |
7 - 16 business days* |
226.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human Secreted Phosphoprotein 1 is produced by our Mammalian... more
Product information "Osteopontin Protein (recombinant human)"
Protein Construction: Recombinant Human Secreted Phosphoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ile17-Asn314 is expressed with a 6His tag at the C-terminus. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 75 kDa. Protein function: Secreted Phosphoprotein 1 (SPP1) is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Based on gene structure and chromosomal location, SPP1 is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), enamelin (ENAM), and matrix extracellular phosphoglycoprotein (MEPE). SPP1 is expressed in bone, although it is also expressed in other tissues. SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones. The fact that SPP1 interacts Protein function: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. [The UniProt Consortium]
Keywords: | SPP1, BNSP, SPP-1, PSEC0156, Uropontin, Osteopontin, Nephropontin, Bone sialoprotein 1, Urinary stone protein, Secreted phosphoprotein 1, Recombinant Human Osteopontin Protein |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH032000 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 34.8 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K06250 | Matching products |
UniProt ID : | P10451 | Matching products |
Gene ID | GeneID 6696 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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