Macrophage Inflammatory protein-5 (CCL15), 68 amino acids, human recombinant (rHuMIP5-68aa)

Macrophage Inflammatory protein-5 (CCL15), 68 amino acids, human recombinant (rHuMIP5-68aa)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97623.5 5 µg - -

3 - 10 business days*

70.00€
97623.25 25 µg - -

3 - 10 business days*

180.00€
97623.1 1 mg - -

3 - 10 business days*

-
 
Macrophage Inflammatory Protein-5 human recombinant produced in E. coli is a single,... more
Product information "Macrophage Inflammatory protein-5 (CCL15), 68 amino acids, human recombinant (rHuMIP5-68aa)"

Macrophage Inflammatory Protein-5 human recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of 7.4 kDa. CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1?, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells. Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED50 for this effect is typically 2 - 4 ng/ml.

Keywords: Small inducible cytokine A15 precursor, CCL15, Macrophage inflammatory protein 5, MIP-5, MIP5, Chemokine CC-2, HCC-2, NCC-3, MIP- 1 delta, Leukotactin-1, LKN-1, Mrp-2b, C-C motif chemokine 15
Supplier: Biomol GmbH
Supplier-Nr: 97623.1

Properties

Application: Cell culture
Conjugate: No
Expressed in: E.coli
Origin: Human
MW: 7400 D
Purity: >97%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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