Leukemia Inhibitory Factor/LIF Protein (recombinant human)

Leukemia Inhibitory Factor/LIF Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH032694.10 10 µg - -

7 - 16 business days*

E-PKSH032694.50 50 µg - -

7 - 16 business days*

Activity: Measured by the M1 cell differentiation assay.The ED50 for this effect is less than 0.8... more
Product information "Leukemia Inhibitory Factor/LIF Protein (recombinant human)"
Activity: Measured by the M1 cell differentiation assay.The ED50 for this effect is less than 0.8 ng/ml Protein Construction: Recombinant Human Leukemia Inhibitory Factor is produced by our E.coli expression system and the target gene encoding Ser23-Phe202 is expressed. Sequence: Ser23-Phe202. Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 18 kDa. Protein function: Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Human and murine mature LIF exhibit a 78% sequence identity at the amino acid level. Human LIF is equally active on human and mouse cells. Murine LIF is approximately 1000 fold less active on human cells than human LIF. Protein function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. [The UniProt Consortium]
Keywords: LIF, MLPLI, HILDA, D factor, Emfilermin, Leukemia inhibitory factor, Melanoma-derived LPL inhibitor, Differentiation-stimulating factor, Recombinant Human Leukemia Inhibitory Factor/LIF Protein
Supplier: Elabscience
Supplier-Nr: E-PKSH032694


Conjugate: No
Expressed in: E.coli
Origin: Human
MW: 19.7 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: +20°C (International: +20°C)
Our products are for laboratory research use only: Not for administration to humans!
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