May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of Lep may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 147 amino acids. The ED50, calculated by the leptin-dependant stimulation of Human OB-R transfected murine BaF3 indicator cells is 0.35-0.06 ng/ml.
|Keywords:||OB Protein, Obesity Protein, OBS, Obesity factor|
|Application:||In vivo assays|
Handling & Safety
|Shipping:||+20°C (International: +20°C)|