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Rat recombinant IP-10 produced in E.coli is a single, non-glycosylated, polypeptide chain... more
Product information "IP-10 (CXCL10), rat recombinant (rrIP-10)"
Rat recombinant IP-10 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8.6kDa. Chemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes and T cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92A.
Keywords: | C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Interferon-inducible protein 10, Protein Mob-1, Small-inducible cytokine B10, Cxcl10, Inp10, Mob1, Scyb10. |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97524 |
Properties
Application: | Cell Culture |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | rat |
MW: | 8600 D |
Purity: | >97% |
Format: | Lyophilized |
Database Information
KEGG ID : | K12671 | Matching products |
UniProt ID : | P48973 | Matching products |
Gene ID | GeneID 245920 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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