Interleukin-2, equine recombinant (reIL-2)

Interleukin-2, equine recombinant (reIL-2)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97647.5 5 µg - -

3 - 10 business days*

70.00€
97647.20 20 µg - -

3 - 10 business days*

180.00€
97647.1 1 mg - -

3 - 10 business days*

-
 
Recombinant equine Interleukin-2 produced in E. coli is a single, non-glycosylated, polypeptide... more
Product information "Interleukin-2, equine recombinant (reIL-2)"

Recombinant equine Interleukin-2 produced in E. coli is a single, non-glycosylated, polypeptide chain containing 129 amino acids (with a substitution of S for C - at position 141 compared with the wild type IL2) and having a molecular mass of 14.9 kDa. IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 1.0 µg/ml, corresponding to a specific activity of > 1000 IU/mg.

Keywords: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.
Supplier: Biomol GmbH
Supplier-Nr: 97647.1

Properties

Application: Cell culture
Conjugate: No
Expressed in: E.coli
Origin: Horse
MW: 14900 D
Purity: >97%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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