Interleukin-13, Rhesus Macaque recombinant (rrmIL-13)

Interleukin-13, Rhesus Macaque recombinant (rrmIL-13)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97595.2 2 µg - -

3 - 10 business days*

70.00€
97595.10 10 µg - -

3 - 10 business days*

180.00€
97595.1 1 mg - -

3 - 10 business days*

-
 
Rhesus Macaque recombinant IL 13 produced in E.coli is a single, non-glycosylated, polypeptide... more
Product information "Interleukin-13, Rhesus Macaque recombinant (rrmIL-13)"

Rhesus Macaque recombinant IL 13 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 114 amino acids and having a molecular mass of 12.6kDa. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B-cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL-3, IL-5, IL-4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-4.

Keywords: IL13, IL-13, Interleukin-13
Supplier: Biomol GmbH
Supplier-Nr: 97595

Properties

Application: Cell Culture
Conjugate: No
Expressed in: E.coli
Origin: Rhesus Macaque
MW: 12600 D
Purity: >97%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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