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Human recombinant IL-12 p40 produced in Hi-5 cell using Baculovirus is a single polypeptide chain containing 315 amino acids (23-328) and having a molecular mass of 29.4kDa. Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation.
Keywords: | NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF, Edodekin-alpha, IL-12 p40, IL-12B, IL-12 subunit p40, NK cell stimulatory factor chain 2. |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97492.1 |
Properties
Application: | Bioassay |
Conjugate: | No |
Expressed in: | Insect cells |
Origin: | Human |
MW: | 35800 D |
Purity: | >90% |
Format: | Solution |
Database Information
KEGG ID : | K05425 | Find alternatives |
UniProt ID : | P29460 | Find alternatives |
Gene ID | GeneID 3593 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |