Insulin Protein (recombinant human)

Insulin Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH032458.100 100 µg -

7 - 16 business days*

869.00€
 
Activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer... more
Product information "Insulin Protein (recombinant human)"
Activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells.The ED50 for this effect is typically 0.2-1 µg/mL. Protein Construction: A DNA sequence encoding human insulin B chain (2LGB_B)(Phe1-Lys29) and human insulin A chain (2KXK_A)(Gly1-Asn21) was expressed with a linker AAK. Sequence: Phe1-Lys29. Endotoxin: Please contact us for more information. Apparent Molecular Mass: 6 kDa. Protein function: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy Protein function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. [The UniProt Consortium]
Keywords: INS, Recombinant Human Insulin Protein
Supplier: Elabscience
Supplier-Nr: E-PKSH032458

Properties

Conjugate: No
Host: Yeast
Species reactivity: human
MW: 6 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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