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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH032458.100 | 100 µg | - |
7 - 16 business days* |
869.00€
|
Activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer... more
Product information "Insulin Protein (recombinant human)"
Activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells.The ED50 for this effect is typically 0.2-1 µg/mL. Protein Construction: A DNA sequence encoding human insulin B chain (2LGB_B)(Phe1-Lys29) and human insulin A chain (2KXK_A)(Gly1-Asn21) was expressed with a linker AAK. Sequence: Phe1-Lys29. Endotoxin: Please contact us for more information. Apparent Molecular Mass: 6 kDa. Protein function: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy Protein function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. [The UniProt Consortium]
Keywords: | INS, Recombinant Human Insulin Protein |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH032458 |
Properties
Conjugate: | No |
Host: | Yeast |
Species reactivity: | human |
MW: | 6 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K04526 | Matching products |
UniProt ID : | P01308 | Matching products |
Gene ID | GeneID 3630 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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