Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)

Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97305.2 2 µg - -

3 - 10 business days*

280.00€
97305.5 5 µg - -

3 - 10 business days*

430.00€
97305.10 10 µg - -

3 - 10 business days*

780.00€
97305.1 1 mg - -

3 - 10 business days*

-
 
The insulin-like growth factors, isolated from plasma, are structurally and functionally related... more
Product information "Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)"

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003).

Keywords: Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF
Supplier: Biomol GmbH
Supplier-Nr: 97305

Properties

Application: Bioassay
Conjugate: No
Expressed in: E.coli
Origin: Human
Format: Purified

Database Information

KEGG ID : K05459 | Find alternatives
UniProt ID : P05019 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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