Product information "IL1F10, Recombinant, Human, aa1-152, His-SUMO-Tag (Interleukin-1 Family Member 10)"
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. Source: Recombinant protein corresponding to aa1-152 from human IF1F10, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~32.9kD, AA Sequence: MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICILPNRGLARTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFEQSW, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
IL-38, FIL1T, FKSG75, IL1F10, IL-1HY2, IL-1F10, FIL1 theta, IL-1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1 theta, Family of interleukin 1-theta, Interleukin-1 family member 10