IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)

IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-MF-12004-C010 10 µg - -

3 - 9 business days

215.00€
CHI-MF-12004-C050 50 µg - -

3 - 9 business days

385.00€
CHI-MF-12004-5010 50 µg - -

3 - 9 business days

759.00€
 
The extracellular domain of mouse IL-4 (aa 21-140) is fused at the C-terminus to the Fc portion... more
Product information "IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)"
The extracellular domain of mouse IL-4 (aa 21-140) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
Keywords: Il4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1, B-cell IgG differentiation factor
Supplier: Chimerigen Laboratories
Supplier-Nr: MF-12004-C010

Properties

Application: Bioassays
Conjugate: No
Expressed in: Mouse cells
Origin: Mouse
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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