IL-1 alpha (IL-1F1), ovine recombinant (rovIL-1alpha)

Produced in Yeast. Amino acid sequence: SAHYSFQSNV KYNFMRVIHQ ECILNDALNQ SIIRDMSGPY LTAATLNNLE EAVKFDMVAY VSEEDSQLPV TLRISKTQLF VSAQNEDEPV LLKEMPETPK IIKDETNLLF FWEKHGSMDY FKSVAHPKLF IATKQEKLVH MASGPPSITD FQILEK (156). Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [The UniProt Consortium]