I-309 (CCL1) His Tag, human recombinant (rHuI-309-His)

Human recombinant I-309 fused with a 21 amino acid His tag at N-terminus produced in E.coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids (24-96) and having a molecular mass of 10.8kDa. Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. This chemokine resides in a large cluster of CC chemokines on human chromosome 17.