FGF-21 (mouse) (rec.)

FGF-21 (mouse) (rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-MF-102FGF21-C010 10 µg - -

3 - 9 business days*

226.00€
CHI-MF-102FGF21-C050 50 µg - -

3 - 9 business days*

523.00€
 
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has... more
Product information "FGF-21 (mouse) (rec.)"
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity. FGF-21 lacks the heparin-binding domain of most FGF proteins, allowing its secretion. FGF-21 is abundantly expressed in adipose tissues, liver and pancreas. In adipose tissue, FGF-21 promotes glucose uptake and oxidation and in liver it replenishes on fasting the tissues with fuel on low nutritional supply. It also induces lipolysis and ketogenesis. FGF-21 acts through FGF receptors (FGFR) associated with the auxiliary protein beta-Klotho. Recently, FGF-21 has been reported to interact directly with the brain circadian clock to coordinate activity and reproduction as part of the adaptation to fasting. Due to its multiple functions of normalizing glucose, lipid and energy homeostasis, FGF-21 represents an attractive novel therapy for type 2 diabetes mellitus and obesity.
Keywords: Fgf21, FGF-21, Fibroblast growth factor 21
Supplier: Chimerigen Laboratories
Supplier-Nr: MF-102FGF21

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: mouse
MW: ~23 kD
Purity: >90%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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