FGF-2 (human) (rec.)

FGF-2 (human) (rec.)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40B-0150-C010 10 µg -

3 - 9 business days*

10 %
127.00€
114.30€
AG-40B-0150-3010 30 µg (3 x 10 µg) -

3 - 9 business days*

10 %
253.00€
227.70€
 
Human FGF-2 (aa 131-288) is untagged. Endotoxin Content: <0.1EU/?g purified protein (LAL test,... more
Product information "FGF-2 (human) (rec.)"
Human FGF-2 (aa 131-288) is untagged. Endotoxin Content: <0.1EU/?g purified protein (LAL test, Lonza). FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signaling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
Keywords: FGF2, bFGF, FGFB, FGF-2, HBGF-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0150

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 18 kD
Purity: >95%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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