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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH033848.10 | 10 µg | - |
7 - 16 business days* |
139.00€
|
|||
E-PKSH033848.50 | 50 µg | - |
7 - 16 business days* |
412.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human Protein FAM3B is produced by our Mammalian expression... more
Product information "FAM3B (C-Fc) (recombinant human)"
Protein Construction: Recombinant Human Protein FAM3B is produced by our Mammalian expression system and the target gene encoding Glu30-Ser235 is expressed with a Fc tag at the C-terminus. Sequence: Glu30-Ser235. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 50-65 kDa. Protein function: FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death. Protein function: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. [The UniProt Consortium]
Keywords: | FAM3B, PRED44, PANDER, C21orf11, Protein FAM3B, Pancreatic-derived factor, Cytokine-like protein 2-21, Recombinant Human FAM3B (C-Fc) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH033848 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 50 kD |
Format: | Lyophilized |
Database Information
UniProt ID : | P58499 | Matching products |
Gene ID | GeneID 54097 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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