Epigen, active (EPGN, Epithelial mitogen), Recombinant, Human

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 300ng/ml, corresponding to a specific activity of ?3.3x10e3 IU/mg. Sequence: AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA, Molecular Weight: 7.9kD, PubMed ID: 12975309, 14702039, 15340161, 15611079, Gene Name: EPGN,UNQ3072/PRO9904, Swiss Prot: Q6UW88, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.