EGF, Recombinant, Rat (Epidermal Growth Factor)

EGF, Recombinant, Rat (Epidermal Growth Factor)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
499939.1 1 mg - -

1 - 19 business days

-
499939.100 100 µg - -

1 - 19 business days

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Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in... more
Product information "EGF, Recombinant, Rat (Epidermal Growth Factor)"
Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites. EGF receptors are expressed in almost all types of tissues. Parietal endoderm, mature skeletal muscles, and hematopoietic tissues do not express the receptor. The EGF receptor, designated HER1, is a 170kD transmembrane glycoprotein with a length of 1186aa. It is identical with a previously described glycoprotein called SA-7 (species antigen 7). The extracellular receptor domain has a length of 621aa, including 11 glycosylated asparagine residues and 51 cysteine residues. This domain contains the EGF binding site and also binds mammalian TGF-alpha. Source: Recombinant protein corresponding to rat EGF expressed in E. coli. Molecular Weight: ~6.2kD, Biological Activity: The ED50 was determined by the dose-dependent proliferation of NIH3T3 cells and was found to be <0.5ng/mL. Endotoxin: <1EU/ug (LAL), Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Egf
Supplier: United States Biological
Supplier-Nr: 499939

Properties

Conjugate: No
MW: 6,2
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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