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Human recombinant CYR61 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 357 amino acids and having a molecular mass of 39.5kDa. CYR61 is a growth factor-inducible, immediate-early gene that has multifaceted activities in various cancers. CYR61 is a secreted, cysteine-rich, heparin-binding protein which is encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and enhances growth factor-induced DNA synthesis in the same cell type.
|Keywords:||CYR61, Protein CYR61, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IGF-binding protein 10, IGFBP-10, IBP-10, Protein GIG1, CCN family member 1, CCN1, GIG1, IGFBP10.|
|KEGG ID :||K06829 | Find alternatives|
|UniProt ID :||O00622 | Find alternatives|
|Gene ID||GeneID 3491 | Find alternatives|
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