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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40A-0050Y-C010 | 10 µg | - |
3 - 9 business days* |
193.00€
|
|||
AG-40A-0050Y-C050 | 50 µg | - |
3 - 9 business days* |
352.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Signal peptide sequence and the human secretory clusterin (aa 1-449) are fused at the C-terminus... more
Product information "Clusterin (secretory form) (human) (rec.)"
Signal peptide sequence and the human secretory clusterin (aa 1-449) are fused at the C-terminus to a FLAG(R)-tag. Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
Keywords: | TRPM-2, Apolipoprotein J, APO-J, CLI, CLU, SGP-2, APOJ, AAG4 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40A-0050Y |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 39/40 kD |
Purity: | >90% |
Format: | Lyophilized |
Database Information
KEGG ID : | K17252 | Matching products |
UniProt ID : | P10909 | Matching products |
Gene ID | GeneID 1191 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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