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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH033901.10 | 10 µg | - |
7 - 16 business days* |
242.00€
|
|||
E-PKSH033901.50 | 50 µg | - |
7 - 16 business days* |
725.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian... more
Product information "C-X-C Motif Chemokine 6/CXCL6 (C-6His) (recombinant human)"
Protein Construction: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian expression system and the target gene encoding Gly38-Asn114 is expressed with a 6His tag at the C-terminus. Sequence: Gly38-Asn114. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 13 kDa. Protein function: Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60% and 67% aa identity with mouse and bovine CXCL6, respectively. Protein function: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). [The UniProt Consortium]
Keywords: | GCP2, CXCL6, Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH033901 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 9.35 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K05506 | Matching products |
UniProt ID : | P80162 | Matching products |
Gene ID | GeneID 6372 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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