Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH032188.10 | 10 µg | - |
7 - 16 business days* |
170.00€
|
|||
E-PKSH032188.50 | 50 µg | - |
7 - 16 business days* |
495.00€
|
Protein Construction: Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli... more
Product information "C-C Motif Chemokine 16/CCL16 Protein (recombinant human)"
Protein Construction: Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed. Sequence: Gln24-Gln120. Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 14 kDa. Protein function: CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells. Protein function: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. [The UniProt Consortium]
Keywords: | LMC, LCC-1, MTN-1, CCL16, NCC-4, HCC-4, ILINCK, Monotactin-1, Chemokine LEC, Chemokine CC-4, C-C motif chemokine 16, Liver-expressed chemokine, IL-10-inducible chemokine, Small-inducible cytokine A16, Lymphocyte and monocyte chemoattractant, Recombinant H |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH032188 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 11.0 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K21093 | Matching products |
UniProt ID : | O15467 | Matching products |
Gene ID | GeneID 6360 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed