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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSM040952.100 | 100 µg | - |
7 - 16 business days* |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Activity: Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts.The... more
Product information "bFGF / FGF2 Protein (His Tag) (recombinant mouse)"
Activity: Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts.The ED50 for this effect is typically 0.1-0.6 ng/mL. Protein Construction: A DNA sequence encoding the mouse Fgf2 (NP_032032.1) (Ala11-Ser154) was expressed with a polyhistidine tag at the N-terminus. Sequence: Ala11-Ser154. Fusion tag: N-His Endotoxin: Please contact us for more information. Protein function: Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies. bFGF/FGF2 Protein & Antibody Products Protein function: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. [The UniProt Consortium]
Keywords: | bFGF, Fgf2, Fgf-2, FGF-2, HBGF-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2, Recombinant Mouse bFGF / FGF2 Protein (His Tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSM040952 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | mouse |
MW: | 18.5 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K18497 | Matching products |
UniProt ID : | P15655 | Matching products |
Gene ID | GeneID 14173 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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