Angiopoietin Like Protein 3, human recombinant, HEK (rhuANG-5)

Angiopoietin Like Protein 3, human recombinant, HEK (rhuANG-5)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
99929.2 2 µg - -

3 - 10 business days*

70.00€
99929.10 10 µg - -

3 - 10 business days*

180.00€
99929.100 100 µg - -

3 - 10 business days*

1,680.00€
 
ANGPTL3 and ANGPTL4 are angiopoietin-like proteins secreted and expressed mainly by the liver,... more
Product information "Angiopoietin Like Protein 3, human recombinant, HEK (rhuANG-5)"

ANGPTL3 and ANGPTL4 are angiopoietin-like proteins secreted and expressed mainly by the liver, their role being the regulation of triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. During different nutritional states (feeding/fasting) the levels of the circulating triglycerides are regulated by Angptl3 and Angptl4 through differential inhibition of Lipoprotein lipase (LPL) as shown by the experimental data. The molecular structure of ANGPTL3 is similar to that of the angiopoietins (vascular endothelial growth factors). Deletion mutants of human Angiopoietin 5 were used in order to demonstrate that the N-terminal domain (fragment 17-207) and not the C-terminal fibrinogen-like domain (fragment 207-460) increased the plasma triglyceride levels in mice.

Keywords: ANG-5, ANGPT5, ANGPTL3, Angiopoietin-5, Angiopoietin-like protein 3, Angiopoietin-related protein 3
Supplier: Biomol GmbH
Supplier-Nr: 99929.2

Properties

Application: Bioassay
Conjugate: No
Expressed in: Human cells
Origin: Human
MW: 52,6 kD
Purity: >95%

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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