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Product information "Angiopoietin-1, human recombinant (rHuANG-1)"
Human recombinant ANGPT1 produced in E.coli is a single, non-glycosylated polypeptide chain containing 480 amino acids (20-498) and having a molecular mass of 55.6 kDa. ANGPT1 is an angiogenic factor which intervenes in blood vessel maturation and takes part in endothelial development. ANGPT1 is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. The glycosylated ANGPT1 protein has a coiled-coIL-region in the amino terminus and a fibrinogen-like domain at the carboxy terminus.