Growth-regulated protein gamma (GRO gamma), human recombinant, (rHuGRO gamma)

Growth-regulated protein gamma (GRO gamma), human recombinant, (rHuGRO gamma)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G8975-25.2 2 µg - -

3 - 19 business days*

263.00€
G8975-25.10 10 µg - -

3 - 19 business days*

402.00€
 
CXCL3/GROg is a small cytokine belonging to the CXC chemokine family. CXCL3 controls migration... more
Product information "Growth-regulated protein gamma (GRO gamma), human recombinant, (rHuGRO gamma)"
CXCL3/GROg is a small cytokine belonging to the CXC chemokine family. CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. The three GRO cDNAs encode 107 amino acid precursor proteins from which the N-terminal 34 amino acid residues are cleaved to generate the mature GROs. There are no potential N-linked glycosylation sites in the amino acid sequences. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B. GRO gamma Recombinant, Human is a 7.9kD protein containing 73 amino acid residues. , Source: E. coli, Form: Lyophilized protein without additives. Stability: The lyophilized protein, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted rat GRO-gamma should be stored in working aliquots at -20°C. Purity: > 98% by SDS-PAGE and HPLC analyses. Endotoxin: < 0.1ng/ug. Reconstitution: Soluble in water and most aqueous buffers. The lyophilized protein should be reconstituted in water to a concentration of 100ng/ul. This solution can be diluted into water or other buffered solutions or stored at -20°C for future use. Biological Activity: Maximal chemotactic activity on rat neutrophils is assayed in a modified Boyden chamber at 50ng/ml. Responding Cells (partial list): Neutrophils , Concentration Range for most in vitro applications: 10-100ng/ml, , Country of Origin: USA
Supplier: United States Biological
Supplier-Nr: G8975-25

Properties

Conjugate: No
Expressed in: Human source
Origin: Human
Format: Molecular Biology Grade

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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