Cytokines

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF),... read more »
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Cytokines

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

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Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)
Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)

Item number: 52624.5

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain...
Keywords: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Application: Cell culture
Expressed in: E.coli
Origin: Mouse
MW: 17.3 kD
From 70.00€ *
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Stromal Cell-Derived Factor-1 alpha (CXCL12), human recombinant (rHuSDF-1a)
Stromal Cell-Derived Factor-1 alpha (CXCL12), human...

Item number: 94842.10

Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface...
Keywords: SDF-1, CXCL12, Pre-B cell growth-stimulating factor, PBSF, hIRH, chemokine (C-X-C motif) ligand 12, SDF1, SDF1A, TPAR1,...
Application: Chemoattract.
Expressed in: E.coli
Origin: Human
MW: 8004.00 D
From 71.00€ *
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Interleukin-1 beta (IL-1 beta), human recombinant (HumaXpress)
Interleukin-1 beta (IL-1 beta), human recombinant...

Item number: HZ-1164

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin <0.1EU/µg.
Keywords: HZ-11641000ug (rHuIL-1-beta), IL1B, IL1F2, Interleukin-1 beta, Catabolin
Application: Cell culture, Bioassays
Expressed in: Human cells
Origin: Human
0.00€ *
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TNF-Related Apoptosis Inducing Ligand/Apo2L, human recombinant (rHuTRAIL)
TNF-Related Apoptosis Inducing Ligand/Apo2L, human...

Item number: 87359.50

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis....
Keywords: Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand,...
Application: Cell Culture
Expressed in: E.coli
Origin: Human
MW: 19600.00 D
From 70.00€ *
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Interleukin-4, human recombinant (rHuIL-4-CHO)
Interleukin-4, human recombinant (rHuIL-4-CHO)

Item number: 94906.10

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the...
Keywords: BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra
Application: Cell biology studies
Expressed in: Hamster cells
Origin: Human
MW: 14000.00 D
From 70.00€ *
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Transforming Growth Factor beta1, GST Tag, human recombinant (rHuTGF-b1-GST)
Transforming Growth Factor beta1, GST Tag, human...

Item number: 76861.10

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of...
Keywords: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB
Expressed in: E.coli
Origin: Human
MW: 35 kD
From 70.00€ *
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Interferon gamma, mouse recombinant (rmIFN-gamma)
Interferon gamma, mouse recombinant (rmIFN-gamma)

Item number: 87389.20

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects...
Keywords: Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma
Application: Cell Culture
Expressed in: E.coli
Origin: Mouse
MW: 15.6 kD
From 70.00€ *
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Progranulin (human) (rec.) (untagged)
Progranulin (human) (rec.) (untagged)

Item number: AG-40A-0188Y-C050

Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
Keywords: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Application: Cell culture
Expressed in: Human cells
Origin: Human
MW: 74 kD
From 187.00€ *
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CCL5/RANTES (human, recombinant)
CCL5/RANTES (human, recombinant)

Item number: Cay32858-100

Chemokine (C-C motif) ligand 5 (CCL5), also known as RANTES, is a pro-inflammatory chemokine and member of the CC subfamily of chemokines. It is composed of an unstructured N-terminal region, a flexible loop, a 310-helix, three strands of an antiparallel beta-sheet, and a single C-terminal alpha helix. It is...
Keywords: CCL5, EoCP, TCP228, D17S136E, SIS-delta, RANTES(3-68), RANTES(4-68), C-C motif chemokine 5, Small-inducible cytokine A5, T...
Expressed in: E. coli
From 244.00€ *
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Stem Cell Factor, mouse recombinant (rmSCF)
Stem Cell Factor, mouse recombinant (rmSCF)

Item number: 94908.10

Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins. (www.uniprot.org) Produced in E.coli as a single,...
Keywords: Kit ligand, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250, Hematopoietic growth factor...
Application: Cell culture
Expressed in: E.coli
Origin: Mouse
MW: 18309.00 D
From 70.00€ *
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Transforming Growth Factor Beta-1/TGFB1 (recombinant human)
Transforming Growth Factor Beta-1/TGFB1 (recombinant human)

Item number: E-PKSH033947.10

Protein Construction: Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Leu30-Arg278(Cys33Ser) is expressed. Sequence: Leu30-Arg278(Cys33Ser). Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 20-30 kDa....
Keywords: TGFB, Recombinant Human Transforming Growth Factor Beta-1/TGFB1
Expressed in: Human cells
Origin: Human
MW: 28.5 kD
From 169.00€ *
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Interleukin-1 beta, mouse recombinant (rmIL-1-beta)
Interleukin-1 beta, mouse recombinant (rmIL-1-beta)

Item number: 50441.10

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release...
Keywords: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear...
Application: Cell culture
Expressed in: E.coli
Origin: Mouse
MW: 17500.00 D
From 70.00€ *
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