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Vascular Endothelial Growth Factor-165, human recombinant...
Item number: 97324.10
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
| Keywords: | Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609 |
| Application: | Cell Culture |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 40 kD |
From 94.00€
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Interleukin-1 beta, human recombinant (rHuIL-1-beta)
Item number: 94886.10
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release...
| Keywords: | Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear... |
| Application: | Cell biology studies |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 17.0 kD |
From 94.00€
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Activin-A, active, human recombinant
Item number: 97394.10
Human recombinant Activin-A, active form, produced in E.coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa. Activins are homodimers or heterodimers of the different beta subunit isoforms, part of the TGFbeta family. Mature Activin A has...
| Keywords: | Inhba, Inhibin beta A, FSH releasing protein. |
| Application: | Cell Culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 26.2 kD |
From 94.00€
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Vascular Endothelial Growth Factor-165, human recombinant...
Item number: 87399.10
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
| Keywords: | Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609 |
| Application: | Cell Culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 38.2 kD |
From 94.00€
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Brain Derived Neurotrophic Factor, human recombinant...
Item number: 52615.10
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses...
| Keywords: | BDNF, MGC34632 |
| Application: | Cell culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 27000.00 D |
From 94.00€
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Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)
Item number: 52624.5
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain...
| Keywords: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2 |
| Application: | Cell culture |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 17.3 kD |
From 94.00€
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Sonic HedgeHog, human recombinant (rHuSHH)
Item number: 97290.25
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
| Keywords: | SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5 |
| Application: | Cell culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 19683 D |
From 94.00€
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Stromal Cell-Derived Factor-1 alpha (CXCL12), human...
Item number: 94842.10
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface...
| Keywords: | SDF-1, CXCL12, Pre-B cell growth-stimulating factor, PBSF, hIRH, chemokine (C-X-C motif) ligand 12, SDF1, SDF1A, TPAR1,... |
| Application: | Chemoattract. |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 8004.00 D |
From 94.00€
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Progranulin (human) (rec.) (untagged)
Item number: AG-40A-0188Y-C050
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
| Keywords: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 74 kD |
From 215.00€
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TNF-beta (human, recombinant)
Item number: Cay40210-1
TNF-beta, also known as lymphotoxin-alpha (LT-alpha), is a cytokine and member of the TNF and TNF receptor (TNFR) cytokine superfamily. It is produced as an N-glycosylated peptide that forms soluble bell-shaped homotrimers after signal peptide cleavage. TNF-beta also forms cell surface-anchored heterotrimers with...
| Keywords: | LTA, TNFB, LT-alpha, TNF-beta, LT-alpha, TNF-beta, Lymphotoxin-alpha, Lymphotoxin-alpha, Tumor necrosis factor ligand... |
| Application: | Active |
From 467.00€
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Lymphotoxin-beta (cynomolgus monkey, recombinant)
Item number: Cay40211-50
Lymphotoxin-beta (LT-beta), also known as TNF-C, is a member of the TNF and TNF receptor (TNFR) cytokine superfamily. It is a type II transmembrane protein that forms heterotrimers with TNF-beta, also known as LT-alpha, which bind to the LT-beta receptor (LT-betaR). LT-beta is expressed in T cells, natural killer...
| Keywords: | LTB, LT-beta, Lymphotoxin-beta, Tumor necrosis factor C, Tumor necrosis factor ligand superfamily member 3 |
399.00€
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Soluble Fas Ligand/CD95 Ligand (human, recombinant, aa...
Item number: Cay40212-1
Fas ligand (FasL), also known as CD95L, is a type II transmembrane protein and member of the TNF superfamily. It is composed of a cytoplasmic domain, transmembrane domain, stalk region, TNF homology domain (THD), which is involved in homotrimerization, and Fas-binding domain. FasL is expressed in activated T cells,...
| Keywords: | APL, SPA, APTL, FasL, FASLG, CD178, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble... |
| Application: | Active |
From 319.00€
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