NOP10 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 195 Sequence: atgtttctcc agtattacct caacgagcag ggagatcgag tctatacgct gaagaaattt gacccgatgg gacaacagac ctgctcagcc catcctgctc ggttctcccc agatgacaaa tactctcgac accgaatcac catcaagaaa cgcttcaagg tgctcatgac ccagcaaccg cgccctgtcc Protein function: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. [The UniProt Consortium]