CRBN Molecular Glues Library

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-L9800-10uL	10 µl (10 µL x 10 mM (in DMSO))	-	-	-	7 - 10 business days*	-
TGM-L9800-25uL	25 µl (25 µL x 10 mM (in DMSO))	-	-	-	7 - 10 business days*	-
TGM-L9800-50uL	50 µl (50 µL x 10 mM (in DMSO))	-	-	-	7 - 10 business days*	-
TGM-L9800-100uL	100 µl (100 µL x 10 mM (in DMSO))	-	-	-	7 - 10 business days*	-
TGM-L9800-200uL	200 µl (200 µL x 10 mM (in DMSO))	-	-	-	7 - 10 business days*	-

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Description: - A collection of 4,775 newly designed and synthesized molecular glue structures,... more

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Product information "CRBN Molecular Glues Library"

Description: - A collection of 4,775 newly designed and synthesized molecular glue structures, suitable for research on CRBN-targeting molecular glue drugs, - Selected CRBN warheads with reported experimental validation, further optimized using an AI-driven molecular generation system to design highly reliable candidate CRBN-targeting molecular glues, - In addition to lenalidomide-like scaffolds, the library includes diverse non-lenalidomide spirocyclic frameworks, offering new opportunities for novel scaffold discovery, - Undergone structural diversification and drug-likeness filtering, ensuring good structural representativeness and favorable druggability properties, - Validated through small-scale random screening, demonstrating a significantly higher hit rate compared to CRBN warhead compounds from other commercial sources.