JWH 018 N-pentanoic acid metabolite-d5

JWH 018 N-pentanoic acid metabolite-d5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 018 N-pentanoic acid metabolite (Cay-9000856) by GC- or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06. JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-pentanoic acid metabolite is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated.Formal Name: 5-(3-(1-naphthoyl)-1H-indol-1-yl-2,4,5,6,7-d5)pentanoic acid. CAS Number: 2748533-42-6. Molecular Formula: C24H16D5NO3. Formula Weight: 376.5. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml. lambdamax: 218, 246, 315 nm. SMILES: O=C(C1=C([2H])N(CCCCC(O)=O)C2=C1C([2H])=C([2H])C([2H])=C2[2H])C3=C4C(C=CC=C4)=CC=C3. InChi Code: InChI=1S/C24H21NO3/c26-23(27)14-5-6-15-25-16-21(19-11-3-4-13-22(19)25)24(28)20-12-7-9-17-8-1-2-10-18(17)20/h1-4,7-13,16H,5-6,14-15H2,(H,26,27)/i3D,4D,11D,13D,16D. InChi Key: BYIVGHIYNFQIJX-HXXXRZHPSA-N.