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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay26761-500 | 500 µg | - |
6 - 10 business days* |
163.00€
|
|||
Cay26761-1 | 1 mg | - |
6 - 10 business days* |
308.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Zileuton-d4 is intended for use as an internal standard for the quantification of zileuton... more
Product information "Zileuton-d4"
Zileuton-d4 is intended for use as an internal standard for the quantification of zileuton (Cay-10006967) by GC- or LC-MS. Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor. It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4, Cay-20110) production induced by the calcium ionophore A23187 (Cay-11016) in purified human peripheral blood polymorphonuclear leukocytes (PMNLs, IC50 = 0.6 µM). Zileuton (10 mg/kg, p.o.) prevents antigen challenge-induced increases in specific lung resistance in a sheep model of asthma at 4 to 8 hours post-challenge following administration 2 hours pre-challenge. Formulations containing zileuton have been used in the prophylaxis and chronic treatment of asthma.Formal Name: N-(1-benzo[b]thien-2-ylethyl-d4)-N-hydroxy-urea. CAS Number: 1189878-76-9. Molecular Formula: C11H8D4N2O2S. Formula Weight: 240.3. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: very slightly soluble. SMILES: ON(C(N)=O)C(C([2H])([2H])[2H])([2H])C1=CC2=CC=CC=C2S1. InChi Code: InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)/i1D3,7D. InChi Key: MWLSOWXNZPKENC-CWIRFKENSA-N.
Keywords: | N-(1-benzo[b]thien-2-ylethyl-d4)-N-hydroxy-urea |
Supplier: | Cayman Chemical |
Supplier-Nr: | 26761 |
Properties
Application: | GC-MS, LC-MS, Quantification, Internal standard, 5-LO inhibitor |
MW: | 240.3 D |
Formula: | C11H8D4N2O2S |
Purity: | >99% deuterated forms (d1-d4) |
Format: | Solid |
Database Information
CAS : | 1189878-76-9| Matching products |
KEGG ID : | K00461 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H302, H319 |
P Phrases: | P264, P270, P280, P301+310, P305+351+338, P330, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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