Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006731-5 5 mg -

6 - 10 business days*

Cay10006731-10 10 mg -

6 - 10 business days*

Cay10006731-25 25 mg -

6 - 10 business days*

Cay10006731-50 50 mg -

6 - 10 business days*

Numerous analogs of arachidonoyl ethanolamide (AEA) potentiate its biological activity. This... more
Product information "VDM11"
Numerous analogs of arachidonoyl ethanolamide (AEA) potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty amide acyl hydrolase (FAAH) within the neurons. VDM11 is an AEA transport inhibitor with essentially no activity on either the central cannabinoid receptor (CB1), peripheral cannabinoid receptor (CB2), or the vanilloid receptor 1 (VR1). However, VDM11 inhibits FAAH and monoacylglycerol lipase (MAGL) and may act as an alternative FAAH substrate. At a concentration of 3 µM, VDM11, like AM404, inhibits glutamergic synaptic transmission between hippocampal neurons. The mechanism of this effect may be a direct action on sodium channels. Thus, the use of anandamide analogs as uptake inhibitors and interpretation of the results must be undertaken with care. Formal Name: N-(4-hydroxy-2-methylphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide. CAS Number: 313998-81-1. Molecular Formula: C27H39NO2. Formula Weight: 409.6. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2)(1:2): .25 mg/ml. lambdamax: 202, 231 nm. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)Nc1ccc(O)cc1C. InChi Code: InChI=1S/C27H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(30)28-26-22-21-25(29)23-24(26)2/h7-8,10-11,13-14,16-17,21-23,29H,3-6,9,12,15,18-20H2,1-2H3,(H,28,30)/b8-7-,11-10-,14-13-,17-16-. InChi Key: WUZWFRWVRHLXHZ-ZKWNWVNESA-N.
Keywords: N-(4-hydroxy-2-methylphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Supplier: Cayman Chemical
Supplier-Nr: 10006731


Application: AEA transport inhibitor
MW: 409.6 D
Formula: C27H39NO2
Purity: >98%
Format: Solution

Database Information

CAS : 313998-81-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H334
P Phrases: P210, P233, P240, P241, P242, P243, P261, P280, P284, P303+361+353, P304+341, P342+311, P370+378, P403+235, P501
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