Thromboxane B1

Thromboxane B1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006610-1 1 mg -

3 - 10 business days*

Cay10006610-5 5 mg -

3 - 10 business days*

Cay10006610-10 10 mg -

3 - 10 business days*

Dihomo-g-linolenic acid (DGLA) is one of the 20-carbon fatty acids that can be metabolized to... more
Product information "Thromboxane B1"
Dihomo-g-linolenic acid (DGLA) is one of the 20-carbon fatty acids that can be metabolized to prostaglandins and thromboxanes (TXs) by cyclooxygenases 1 and 2 (COX-1/COX-2). The result of this metabolism in the human platelet yields TXB1. TXB1 is produced in small amounts when DGLA is added to washed suspensions of human platelets, while the major metabolism of this 1-series fatty acid is via 12-lipoxygenase. However, when co-incubated with amounts of ethanol often found in intoxicated humans, the metabolism of DGLA shifts to an enhanced production of TXB1. Urinary TXB1 or its metabolites may thus be a specific biomarker of prior ethanol abuse. Formal Name: 9,11,15-trihydroxy-thrombox-13-en-1-oic acid. CAS Number: 64626-32-0. Molecular Formula: C20H36O6. Formula Weight: 372.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, Methyl Acetate: 10 mg/ml, PBS (pH 7.2): .15 mg/ml. SMILES: O[C@@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C1. InChi Code: InChI=1S/C20H36O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h12-13,15-18,20-22,25H,2-11,14H2,1H3,(H,23,24)/b13-12+/t15-,16-,17-,18+,20?/m0/s1. InChi Key: JSDWWNLTJCCSAV-VZBVYBAISA-N.
Keywords: 9,11,15-trihydroxy-thrombox-13-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10006610


Application: Bioactive lipid assays
MW: 372.5 D
Formula: C20H36O6
Purity: >98%
Format: Solution

Database Information

CAS : 64626-32-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H361
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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