Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay62750-1 1 mg -

6 - 10 business days*

Cay62750-5 5 mg -

6 - 10 business days*

Cay62750-10 10 mg -

6 - 10 business days*

Cay62750-25 25 mg -

6 - 10 business days*

Thioetheramide-PC is a structurally modified phospholipid that functions as a competitive,... more
Product information "Thioetheramide-PC"
Thioetheramide-PC is a structurally modified phospholipid that functions as a competitive, reversible inhibitor of secretory phospholipase A2 (sPLA2). The IC50 value for thioetheramide-PC is 2 µM at a substrate concentration of 0.5 mM. In addition to binding to the catalytic site of sPLA2, thioetheramide-PC also binds to the activator site of this enzyme. The binding of thioetheramide-PC to the activator site is tighter than its binding to the catalytic site. The result of this dual interaction is that at low concentrations thioetheramide-PC may activate phospholipase activity rather than inhibiting it. Formal Name: 1,2-dideoxy-1-(S-hexadecyl)thio-2-(N-hexadecanoyl)amino-sn-glyceryl-3-phosphorylcholine. CAS Number: 116457-99-9. Synonyms: 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine. Molecular Formula: C40H83N2O5PS. Formula Weight: 735.1. Purity: >95%. Formulation: A solution in ethanol. Solubility: 4.25 mM Triton X-100: soluble (per reference), Ethanol: 10 mg/ml (@ roomtemp). SMILES: CCCCCCCCCCCCCCCC(N[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)CSCCCCCCCCCCCCCCCC)=O. InChi Code: InChI=1S/C40H83N2O5PS/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-36-49-38-39(37-47-48(44,45)46-35-34-42(3,4)5)41-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h39H,6-38H2,1-5H3,(H-,41,43,44,45)/t39-/m0/s1. InChi Key: WLWWVTPUDQTUJU-KDXMTYKHSA-N.
Keywords: 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine, 1,2-dideoxy-1-(S-hexadecyl)thio-2-(N-hexadecanoyl)amino-sn-glyceryl-3-phosphorylcholine
Supplier: Cayman Chemical
Supplier-Nr: 62750


Application: SPLA2 inhibitor
MW: 735.1 D
Formula: C40H83N2O5PS
Purity: >95%
Format: Solution

Database Information

CAS : 116457-99-9| Find alternatives
KEGG ID : K01047 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
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