tetranor-12(S)-HETE

tetranor-12(S)-HETE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007207-25 25 µg -

6 - 10 business days*

165.00€
Cay10007207-50 50 µg -

6 - 10 business days*

314.00€
Cay10007207-100 100 µg -

6 - 10 business days*

594.00€
 
12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is... more
Product information "tetranor-12(S)-HETE"
12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major beta-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetranor-12(S)-HETE. Some data indicate it may play a role in controlling the inflammatory response in injured corneas. In some diseases (e.g., Zellweger's Syndrome) peroxisomal abnormalities result in the inability of cells to metabolize 12(S)-HETE, which may be responsible for symptoms of the disease. The tetranor derivative of 12(S)-HETE is available as a research tool for the elucidation of the metabolic fate of its parent compound. Formal Name: 8S-hydroxy-4Z,6E,10Z-hexadecatrienoic acid. CAS Number: 121842-79-3. Molecular Formula: C16H26O3. Formula Weight: 266.4. Purity: >98%. Formulation: A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): .5 mg/ml. lambdamax: 234 nm. SMILES: CCCCC/C=C\C[C@H](O)/C=C/C=C\CCC(O)=O.
Keywords: 8S-hydroxy-4Z,6E,10Z-hexadecatrienoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10007207

Properties

Application: Bioactive lipid assays
MW: 266.4 D
Formula: C16H26O3
Purity: >98%
Format: Solution

Database Information

CAS : 121842-79-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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