PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt)

PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008115-100 100 µg -

3 - 10 business days*

75.00€
Cay10008115-500 500 µg -

3 - 10 business days*

338.00€
Cay10008115-1 1 mg -

3 - 10 business days*

600.00€
 
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane... more
Product information "PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt)"
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns PtdIns-(4,5)-P2 (1,2-dipalmitoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The natural compound is the product of PtdIns-4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade. Formal Name: 1-(1,2-dihexadecanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt. Synonyms: DPPI-4,5-P2, Phosphatidylinositol-4,5-diphosphate C-16. Molecular Formula: C41H78O19P3 . 3Na. Formula Weight: 1036.9. Purity: >98%. Formulation: A lyophilized powder. Solubility: Chloroform: .1 mg/ml, Chloroform:Methanol:Water: 1 mg/ml, Water: 10 mg/ml. SMILES: O=C(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@H]1O)([O-])=O)OC(CCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCC.[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C41H81O19P3.3Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-39-36(44)37(45)40(58-61(47,48)49)41(38(39)46)59-62(50,51)52,,,/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54. InChi Key: STJBVCQNLFXTFJ-OXJUOGSOSA-K. Side Chain Carbon Sum: 32:0.
Keywords: DPPI-4,5-P2, Phosphatidylinositol-4,5-diphosphate C-16, 1-(1,2-dihexadecanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10008115

Properties

Application: Bioactive lipid assays
MW: 1036.9 D
Formula: C41H78O19P3 . 3Na
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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