Prostaglandin H2

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml.Formal Name: 9alpha,11alpha-epidioxy-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid. CAS Number: 42935-17-1. Synonyms: PGH2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >95%. Formulation: (Request formulation change), A solution in acetone. Solubility: Ethanol: 100 mg/ml, PBS pH 7.2: 2 mg/ml. SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@]2(C[C@@]1(OO2)[H])[H]. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-19(17)25-24-18)10-7-4-5-8-11-20(22)23/h4,7,12-13,15-19,21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1. InChi Key: YIBNHAJFJUQSRA-YNNPMVKQSA-N.