Prostaglandin F2alpha isopropyl ester

Prostaglandin F2alpha isopropyl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16030-1 1 mg -

3 - 10 business days*

Cay16030-5 5 mg -

3 - 10 business days*

Cay16030-10 10 mg -

3 - 10 business days*

PGF2alpha isopropyl ester is an ester prodrug of PGF2alpha with enhanced lipid solubility. Due to... more
Product information "Prostaglandin F2alpha isopropyl ester"
PGF2alpha isopropyl ester is an ester prodrug of PGF2alpha with enhanced lipid solubility. Due to better membrane penetration, PGF2alpha isopropyl ester is more suitable than PGF2alpha or PGF2alpha tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2alpha. When administered topically to the eyes of cynomolgus monkeys, a 5 µg dose reduces intraocular pressure by 68% after the fourth day of treatment. Formal Name: 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, isopropyl ester. CAS Number: 53764-90-2. Synonyms: Dinoprost isopropyl ester, PGF2alpha isopropyl ester. Molecular Formula: C23H40O5. Formula Weight: 396.6. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: >30 mg/ml, DMSO: >50 mg/ml, Ethanol: >50 mg/ml, PBS pH 7.2: <50 µg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C23H40O5/c1-4-5-8-11-18(24)14-15-20-19(21(25)16-22(20)26)12-9-6-7-10-13-23(27)28-17(2)3/h6,9,14-15,17-22,24-26H,4-5,7-8,10-13,16H2,1-3H3/b9-6-,15-14+/t18-,19+,20+,21-,22+/m0/s1. InChi Key: FPABVZYYTCHNMK-YNRDDPJXSA-N.
Keywords: Dinoprost isopropyl ester, PGF2alpha isopropyl ester, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
Supplier: Cayman Chemical
Supplier-Nr: 16030


Application: Bioactive lipid assays
MW: 396.6 D
Formula: C23H40O5
Purity: >98%
Format: Solution

Database Information

CAS : 53764-90-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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