Prostaglandin F2alpha ethyl amide

Prostaglandin F2alpha ethyl amide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16016-1 1 mg -

3 - 10 business days

53.00€
Cay16016-5 5 mg -

3 - 10 business days

237.00€
Cay16016-10 10 mg -

3 - 10 business days

420.00€
 
Prostaglandin F2alpha ethyl amide (PGF2alpha-NEt) is an analog of PGF2alpha in which the C-1... more
Product information "Prostaglandin F2alpha ethyl amide"
Prostaglandin F2alpha ethyl amide (PGF2alpha-NEt) is an analog of PGF2alpha in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 µg/g corneal tissue/hr. PGF2alpha-NEt would be expected to show the typical intraocular effects of PGF2alpha free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.
Keywords: Dinoprost ethyl amide, PGF2alpha-NEt, N-ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
Supplier: Cayman Chemical
Supplier-Nr: 16016-1

Properties

Application: Bioactive lipid assays
MW: 381.6 D
Formula: C22H39NO4
Purity: >98%
Format: Solution

Database Information

CAS : 54130-36-8| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336, H360, EUH066
P Phrases: P201, P202, P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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