Prostaglandin F2alpha Ethanolamide MaxSpec(R) Standard

Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007222-100 100 µg -

5 - 10 business days*

117.00€
 
Prostaglandin F2alpha ethanolamide (PGF2alpha-EA) is produced by cyclooxygenase 2 (COX-2)... more
Product information "Prostaglandin F2alpha Ethanolamide MaxSpec(R) Standard"
Prostaglandin F2alpha ethanolamide (PGF2alpha-EA) is produced by cyclooxygenase 2 (COX-2) metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA, Cay-90050), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2alpha-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2alpha-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents. PGF2alpha-EA MaxSpec(R) standard is a quantitative grade standard of PGF2alpha-EA (Cay-16013) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGF2alpha-EA MaxSpec(R) standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. Formal Name: N-(2-hydroxyethyl)-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide. CAS Number: 353787-70-9. Synonyms: Dinoprost Ethanolamide, PGF2alpha-EA. Molecular Formula: C22H39NO5. Formula Weight: 397.5. Purity: >95%. Formulation: A solution in ethanol at 100 µg/ml. SMILES: CCCCCC(O)/C=C/[C@H]1C(O)CC(O)C1C/C=C\CCCC(=O)NCCO. InChi Code: InChI=1S/C22H39NO5/c1-2-3-6-9-17(25)12-13-19-18(20(26)16-21(19)27)10-7-4-5-8-11-22(28)23-14-15-24/h4,7,12-13,17-21,24-27H,2-3,5-6,8-11,14-16H2,1H3,(H,23,28)/b7-4-,13-12+/t17-,18+,19+,20-,21+/m0/s1. InChi Key: XCVCLIRZZCGEMU-WLOFLUCMSA-N.
Keywords: Dinoprost Ethanolamide, PGF2alpha-EA, N-(2-hydroxyethyl)-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
Supplier: Cayman Chemical
Supplier-Nr: 10007222

Properties

Application: Bioactive lipid assays
MW: 397.5 D
Formula: C22H39NO5
Purity: >95%
Format: Solution

Database Information

CAS : 353787-70-9| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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