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Prostaglandin F1alpha (PGF1alpha) is the putative metabolite of dihomo-gamma-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1alpha and PGF2alpha (Cay-16010, Cay-10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. PGF1alpha binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2alpha. It is only half as active as PGF2alpha in inducing human respiratory smooth muscle contractions in vitro.