Prostaglandin E2 Ethanolamide

Prostaglandin E2 Ethanolamide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14012-500 500 µg -

3 - 10 business days*

Cay14012-1 1 mg -

3 - 10 business days*

Cay14012-5 5 mg -

3 - 10 business days*

Cay14012-10 10 mg -

3 - 10 business days*

Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 (Cay-14010) with improved water... more
Product information "Prostaglandin E2 Ethanolamide"
Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 (Cay-14010) with improved water solubility and stability. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA, Cay-90050) and acts as an agonist at E prostanoid (EP) receptors 1-4 (Kis = 2.45, 0.46, 0.2, and 0.51 µM, respectively). It also inhibits indoleamine 2,3-dioxygenase-1 (IDO-1) in THP-1 cells and human monocytes (IC50s = 5.7 and 4.7 µM, respectively). PGE2-EA (10 µM) prevents morphological changes and F-actin rearrangement as well as reduces L-homocysteine-induced NLRP3 inflammasome formation and activation in podocytes. Ex vivo, PGE2-EA reduces luminal damage and lymphocyte infiltration in a human mucosal explant colitis model.
Keywords: Dinoprostone Ethanolamide, PGE2-EA, Prostamide E2, N-(2-hydroxyethyl)-9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
Supplier: Cayman Chemical
Supplier-Nr: 14012-500


Application: EP receptor agonist
MW: 395.5 D
Formula: C22H37NO5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 194935-38-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H360
P Phrases: P201, P202, P264, P270, P280, P330, P301+P310, P308+P313, P405, P501
Our products are for laboratory research use only: Not for administration to humans!
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