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Statistics & Tracking
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Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 µg/ml. Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 µg. PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively. Formal Name: 1,11alpha,15S-trihydroxy-prost-13E-en-9-one. CAS Number: 21562-57-2. Synonyms: 1-hydroxy Prostaglandin E1, PGE1 Alcohol. Molecular Formula: C20H36O4. Formula Weight: 340.5. Purity: >99%. Formulation: A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml. SMILES: O=C1[C@H](CCCCCCCO)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h12-13,16-18,20-22,24H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,20+/m0/s1. InChi Key: CMHCOGHTKXUQKW-KOAZGICHSA-N.