Prostaglandin E1 Alcohol

Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 µg/ml. Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 µg. PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively.Formal Name: 1,11alpha,15S-trihydroxy-prost-13E-en-9-one. CAS Number: 21562-57-2. Synonyms: 1-hydroxy Prostaglandin E1, PGE1 Alcohol. Molecular Formula: C20H36O4. Formula Weight: 340.5. Purity: >99%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml. SMILES: O=C1[C@H](CCCCCCCO)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h12-13,16-18,20-22,24H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,20+/m0/s1. InChi Key: CMHCOGHTKXUQKW-KOAZGICHSA-N.